The Chargers have a 14-8 record in the all-time series with the Colts, which includes a 23-21 home win when the teams played in Week 10 of the 2007 season. Indianapolis has an 0-2 record in regular season games against the Chargers since beating them, 34-31 in OT, in the 2004 season. The Colts last won a game in San Diego in the year 1999.

5dimes.com oddsmakers currently have the San Diego Chargers listed as 1 point betting odds favorite with the games over/under posted at 49 total points. Click here for more football betting odds

Click Here for Indianapolis Colts vs. San Diego Chargers Expert Picks
Winning NFL picks from Touthouse.com Sports Handicappers

Here are some betting trends to consider on November 23rd 2008:
Colts are 5-0-1 ATS in their last 6 games in Week 12.
Colts are 5-1 ATS in their last 6 games after allowing more than 150 yards rushing in their previous game.
Colts are 9-3 ATS in their last 12 games after accumulating more than 150 yards rushing in their previous game.
Chargers are 4-0 ATS in their last 4 home games vs. a team with a winning road record.
Chargers are 4-0 ATS in their last 4 games after accumulating less than 150 yards passing in their previous game.
Chargers are 6-1-1 ATS vs. a team with a winning record.

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