Minnesota Vikings vs. San Francisco 49ers
NFL Preseason Prediction: San Francisco -2.5 -110 odds
Visit Touthouse.com for more football picks from Doug Upstone
Click here for expert NFL preseason betting picks

The Minnesota Vikings offered the most dominate performance of the first week of the NFL preseason, stepping on St. Louis 28-7. There were more impressive score differentials than what Minnesota accomplished, even without grandpa Favre, but the yardage difference was important. The Vikings gained 414 yards compared to the Rams meager total of 150.

In exhibition, whoops, sorry, preseason football, play against any team that out-gained previous opponent by more than 210 yards. This yardage system is tight 27-13 ATS the last 11 seasons. Take San Francisco Sunday Night on NBC.

Off to usually strong 2-1 start in the NFL Preseason, I have one game that stands above the rest and is my GUARANTEED Week 2 blitzkrieg. My top-notch 3* (high number for me in NFLX) selection is in 90+ percent spot and also covers over 77 percent of the time in this precise situation. I don’t make a ton of plays this time of year in football, but I’m documented at over 62 percent since 2003. Take this Winner home Now!

If you enjoyed this article then you may be interested in:

1. Minnesota Vikings vs. San Francisco 49ers Preseason Odds & Pick: August 22nd 2010
2. Free NFL Preseason Picks: Cowboys vs. 49ers Odds: August 29th 2009
3. Free NFL Pick: San Francisco 49ers vs. Dallas Cowboys Odds: August 29th 2009
4. NFL Betting: Minnesota Vikings vs. San Francisco 49ers Odds & Pick: September 27th 2009
5. 2010 NFL Pre-Season: San Francisco 49ers vs. Indianapolis Colts: August 15th 2010